Strengths

Limitations

Alternatives Comparison

SGLang

Better at: prefix reuse, structured output, multi-turn chat, agentic workflows

Weaker at: extreme TTFT under high concurrency, non-NVIDIA hardware

Choose when: workloads have prefix sharing and you need constrained generation

vLLM

Better at: raw TTFT, high concurrency (C++ routing), larger contributor community

Weaker at: prefix reuse, structured output integration

Choose when: unique prompts, extreme latency requirements, no prefix sharing

TensorRT-LLM

Better at: peak NVIDIA throughput, compiled kernel performance

Weaker at: setup time, vendor lock-in, model-specific compilation required

Choose when: maximum throughput on NVIDIA, can afford compilation time

llama.cpp / Ollama

Better at: CPU/edge/consumer hardware, local development, easy setup

Weaker at: throughput, multi-GPU serving, production-grade features

Choose when: local development, edge deployment, no GPU cluster

The Honest Take

Bottom Line SGLang is the best choice when your workload involves multi-turn conversations, shared system prompts, structured output, or agentic workflows -- which covers the majority of production LLM applications. Its RadixAttention provides a genuine, measurable throughput advantage that no competitor matches. However, if your workload is purely single-shot unique prompts with extreme latency requirements, vLLM's C++ routing or TensorRT-LLM's compiled kernels may serve you better. The framework moves fast; pin to stable releases and test upgrades in staging.